Addiction stories – LSD addiction: AN LSD trip down the wrong path

An LSD trip may be fun for a bit, but LSD addiction doesn't sound like any fun at all.**DISCLAIMER: This post has been changed since its original content. Since I Believe the submitted story was fake, I’ve now made this a post about the possibility of developing LSD dependence**

Many of my readers claim that LSD addiction does not exist. Well, They’re simply wrong. LSD dependence (the clinical term for addiction) is certainly out there, though its no doubt rare. To understand why I can make that claim, let’s cover the specifics of what a psychological assessment of dependence requires:

The official definition of addiction

As far as the DSM-IV (the psychological assessment manual) is concerned, dependence on any drug require at least three of the following to occur within a year:

  1. Tolerance, as defined by either of the following:
    • a need for markedly increased amounts of the substance to achieve intoxication or desired effect
    • markedly diminished effect with continued use of the same amount of substance
  2. Withdrawal, as manifested by either of the following:
    • the characteristic withdrawal syndrome for the substance
    • the same (or a closely related) substance is taken to relieve or avoid withdrawal symptoms
  3. The substance is often taken in larger amounts or over a longer period than was intended
  4. There is a persistent desire or unsuccessful efforts to cut down or control substance use
  5. A great deal of time is spent in activities to obtain the substance, use the substance, or recover from its effects
  6. Important social, occupational or recreational activities are given up or reduced because of substance use
  7. The substance use is continued despite knowledge of having a persistent or recurrent physical or psychological problem that is likely to have been caused or exacerbated by the substance (e.g., continued drinking despite recognition that an ulcer was made worse by alcohol consumption)

Now, I’ve taken more than my share of LSD trips before. Actually, I used to sell acid, among many other drugs in my former life. I knew many people who loved acid, mushrooms, and other hallucinogens (including me) but a few cases stand out in particular.

LSD addiction – Hypotheticals and examples

Given the above definition of substance dependence, any number of combinations of symptoms could qualify someone as being dependent on LSD.

  1. Tolerance buildup for the drug is quick and significant. As anyone who’s ever tried to follow one trip with another knows, the second time requires a lot more acid, and any additional trips increase the amount of LSD needed greatly. Tolerance – Check!
  2. Withdrawal from LSD, especially in the wake of repeated exposures (the multiple trips I was talking about before), includes disorientation, difficulty thinking, fatigue, and sometimes perceptual difficulties (problems with hearing, vision). I’ve experienced this myself, but the best example I’ve seen is of a friend who tried to trip continuously for as long as possible – After about a week and a half, she was eating literally a sheet of acid to feel anything (her boyfriend was a dealer, talk about tolerance). When she stopped because her boyfriend cut her off, she had the hardest time finishing sentences, completing thoughts, or following conversations for nearly three months! Withdrawal – Check!
  3. With the above 2 out of the way, any of the other 5 symptoms can serve to complete the LSD dependence picture. Still, though I’ve never met anyone who tried to stop but couldn’t, I have:
    1. Known people who spent a lot of their time and resources (money) chasing down good acid, paying for it, or preparing for and getting involved in activities that involved LSD.
    2. Many of the people I knew began slacking off at work, sometimes being fired, getting far more lax at school, and neglecting any relationships they had with people who were not involved in their LSD use.
    3. Quite a few of the hard-core LSD users I knew told me time and again that they know their LSD use is causing them difficulties (mostly psychological difficulties) but that fact seemed unable to deter them from buying more acid and continuing down the same path.

So does LSD addiction exist?

Obviously, I believe that LSD dependence exists, though it is no doubt rare. As I’ve stated time and again, I am NOT against the use of drugs. However, I think that drug users’ naive approach to many of these issues, including their constant desire to ignore all signs of the negative consequences of drug abuse, is a big part of the problem here. Ingesting drugs is harmful, but knowing that, I believe people should have the choice to harm themselves, though not others. People with drug problems need help, not jails. Still, to make this a reality, we need to do a much better job of educating ourselves about the true effects of drugs.

I’ve seen LSD destroy lives that took years to rebuild. I’m not talking about people locked away in mental institutions thinking they’re an orange (we’ve all heard that story). But I had friends who became completely unable to live and function in society who gave up friends, significant others, and family for a drug that eventually made them crazy. Some of them are back, some aren’t.

All I’m saying is be careful.

Drug use and abuse following terrrorism: Lessons from addiction research

A recent addiction research article combined findings from 31 different studies to assess the impact of large terrorism events on rates of alcohol, cigarettes, and drug use. The researchers noted that most of the studies occurred after the World Trade bombing of September 11th, 2001.

  • After controlling for the level of exposure, type of event, and length since exposure, the evidence suggests that somewhere between 7%-14% of the population affected by the terrorism will show an increase in their rates of alcohol use.
  • For cigarettes smoking, the average is somewhere between 7%-10%.
  • Drug use, including narcotics and prescription medication, increased an average of 16% to as high as 50% or more. There’s no doubt that a large portion of that increase is due to increased prescription drug use, most likely anti-anxiety medication, antidepressants, etc.

Overall, the findings certainly show that a large-scale terrorism event affects the daily life of citizens, especially in terms of their coping using drugs and alcohol. Hindsight is 20/20, but hopefully next time, we’ll be ready to help people deal with such catastrophes while helping them steer away from possible dependence on drugs down the line.

Citation:

DiMaggio, Charles; Galea, Sandro; Li, Guohua (2009) Substance use and misuse in the aftermath of terrorism. A Bayesian meta-analysis. Addiction, Volume 104, 894-904.

Substance use and misuse in the aftermath of terrorism. A Bayesian meta-analysis

Addiction brain effects : Opiate addiction – Heroin, oxycontin and more

Okay, we’ve talked about crystal meth and cocaine and how they affect the brain during drug use. As I mentioned, both cocaine and meth interfere with the way the brain stores and cleans up important neurotransmitters, including, most importantly, Dopamine and Norepinephrine.

opiates-morphine & heroinThe class of drugs known as opiates, which includes morphine, heroin, codeine, and all their derivatives (including oxycontin), acts on the brain in a completely different manner. Since our goal at All About Addiction is to explain drug use and abuse as comprehensively as possible, let’s turn our attention to this opiate addiction next.

Heroin, morphine, oxycontin, vicodin and other opiates

While cocaine and crystal meth work by disrupting the normal functioning of molecules responsible for cleaning up released neurotransmitters, opiates work by activating actual receptors that naturally occuring neurotransmitters activate. Substance like this are known as agonists; they perform the same action (identically as, to a lesser, or greater extent) as a substance the body already manufactures.

In the case of morphine, heroin, and most other opiates, the most important receptors activated are knownOpiate Receptors as µ-opioid receptors. Activation of the µ-opioid receptors is associated with analgesia (suppression of pain), sedation, and euphoria, which makes sense given the relaxing, pleasure inducing effects of opiates.

Natural opioids (also called endogenous opioids), which include endorphins, are used by the body to relieve pain and increase relaxation, especially during periods of extreme stress. These are the chemicals that make sure we can function during accidents, like after breaking our leg…

Opioids and dopamine

Opioids also increase the amount of dopamine in the brain indirectly. As I mentioned in the earlier posts, dopamine is thought to be the reward indicator in the brain. Unlike crystal meth and cocaine, heroin and its relatives increase the activity of dopamine neurons by releasing the hold that other neurons (that use GABA) have on them. Think of this as the release of pressure on a hose spraying water on a lawn. When the pipe is pinched, only so much water can get through, but once the clasp is released, water can flow in greater quantity; this is essentially what opiates do.

Heroin addiction and long term opiate use

Like I said before, this doesn’t sound so bad, does it? All we’re talking about here is the increasing of the functioning of system that already exists in the brain. The problem isn’t so much in the process, the problem starts when this system gets activated for long periods of time.

HeroinHeroin addicts, and other frequent users of opiates complain about the extreme discomfort they feel when they stop using the drugs. This discomfort has been described as the worse case of the flu you could imagine. Doesn’t sound too appealing, does it? In fact, withdrawal symptoms associated with stopping opiate use are at least one of the main reasons many users return to the drug after trying to clean up. This in addition to all the other effects of the drug on the brain to make wanting to stop so much harder.

The reason for the pains and aches? Given the overactivation of its pain suppression system, the body not only reduces its own supply of opioids, but it also turns up the sensitivity on its pain receptors. Heroin users notice this as an increase in tolerance, but they compensate for it by simply using more. However, when they stop, they’re left with a body unable to suppress its own, hyper sensitive pain system. The results are more than uncomfortable, they’re simply excruciating…

Another common complaint of addicts is diarrhea. This, again, is simply the reversal of the constipation caused earlier by heroin’s actions on opioid receptors that are present in the peripheral system (outside the central nervous system).

I’ve heard addicts speak online about the slow recovery from opiate addiction and I want to dispell a myth here:

Opiates DO NOT stay in your system for weeks or months – The drug itself is gone from the body within days. The reason for the continued suffering is the slow adjustment of your brain and body back to the way things were before the drugs. Think of how long the tolerance took to develop… Now play the tape back in reverse. That’s what happening to you. You can help relieve the pain, but know that if you use anything in the opiate family, you’re making the process last much longer…

So, in summary: As usual, the actions of opiates on the body and brain are not all the severe, extreme, or inappropriate. Opiates are still used in medicine for pain suppression, not only because they work, but because the potential for abuse when used in this way are minimal to non-existent. However, as with all drugs, continued, chronic, abusive use of opiates will change the way your body functions in ways that will produce the exact opposite effects of those users like so much. This leaves people not only with possible addiction problems, but also with a terrifyingly uncomfortable return back to normal functioning.

Addiction help

If you need help finding treatment for your own, or a loved one’s addiction, make sure to give our Rehab-Finder a try: It’s the only evidence-based, scientifically created, tool for finding rehab anywhere in the United States!

More CPDD Addiction research: Addiction, exercise, recovery!

Okay, this is probably the last addiction research update I will give focusing on the Reno conference. The rest of the stuff I learned will be incorporated into future posts.

I’ve written before about the relationship between exercise and recovery (see here) and I will surely write more since for me, it was a big part of the equation.

two separate studies at CPDD reaffirmed my belief that exercise can be a very useful tool in addiction recovery.

The first study, conducted in humans, examined the effect of incorporating an extensive exercise routine into a residential, as well as intensive outpatient, addiction treatment program. Their findings showed improved outcomes for participants in the short, as well as long run. These included length of sobriety, subjective assessment of well being, and more. In talking to the researcher, she seemed to believe that at least part of the effect was due to the relief of cravings achieved by allowing patients to focus on something that took effort, rather than simply sitting around.

The second, and to my mind even more interesting, study examined the effect of exercise on cocaine self-administration in rats. Researchers assigned half of their rats to a cage that had a running wheel while the others were assigned to a regular cage. the rats with the running wheel used the device to run an average of 12 kilometers a day! After a week of simply resting in their cages, when transferred to another cage for 2 hours a day, the rats who had the wheel in their cage took less than half as much cocaine as the rats who didn’t have a wheel. the “wheel-rats” were also found to run less after they began the cocaine portion of the experiment, but their cocaine-taking never got near that of the non-exercising rats. It seems that having the exercise did something to reduce the reinforcing power of cocaine.

I have a feeling that future research will show that these finding hold true for other drugs (like crystal meth, heroin, marijuana, cigarettes, and alcohol) and possibly even for behavioral addictions like food addiction, gambling, and sex addiction.

All in all, research seems to be supporting the notion that exercise can play a significant role in recovery from addiction. Whether it be for boredom relief or an actual internal change in the motivating power of drugs, it looks to me as if Addiction + Exercise = Recovery !

Links of the week

Guess what? It’s that time again. Here are some posts by other writers that offer good help for addicts. I know I’ve been slacking on these, but I’ve simply had too many of my own cents to add. It happens often.

Trudging the gentle path: Being an atheist in recovery

Spiritual River: A new recovery eBook

Stop eating disorders: How to stop a binge

About.com: Signs of a relpase (I don’t necessarily agree with all of these, but it’s a good article)

Addiction Recovery Basics: Sign of addiction

That’s it for now, enjoy!

And don’t forget to click the title of the post for related articles on allaboutaddiction.com that offer addiction help!